Yearly Archives: 2025

Intra-aortic balloon pump (IABP) implantation in the perioperative period of cardiac surgery is an auxiliary treatment for cardiogenic shock. However, there is a lack of effective prediction models for preoper...

The systematic review determines whether valve-sparing surgeries improve patient outcomes compared with non valve-sparing surgeries for tetralogy of Fallot. Although previous studies have reported superior out...

Bioprosthetic heart valves (BHVs) offer advantages over mechanical valves but are limited by long-term degeneration and calcification. This study aimed to develop a durable BHV material using decellularized bovine pericardium (BP) and alternative cross-linking strategies. BP was decellularized using a combination of sodium deoxycholate (SDC) and Triton X-100 (TX), which removed cellular components while preserving the extracellular matrix (ECM), as confirmed by histological, DNA quantification,...

CONCLUSION: The 3D in vitro model established in this study effectively mimics calcification in TE material constructs, aiding in systematic testing and comparison of cardiovascular TE materials. It can help understand calcification principles and evaluate potential risk factors (e.g., strain). As such, the model will support the design of biomaterials for in situ HVTE in particular and implantable polymer grafts in general.

In recent years, the use of Left Ventricular Assist Devices (LVAD) in the treatment of heart failure has been increasingly widespread. Not only do they provide circulatory support for patients, but the reverse...

Prosthetic valves derived from bovine pericardium (BP) are crucial for heart valve replacement, yet current crosslinking methods with glutaraldehyde can lead to immune responses and calcification. This study evaluated the effects of reducing the glutaraldehyde crosslinking time from 10 to 5 days in bovine pericardial patches for use as heart valve substitutes. In addition to examining the physical properties of the BP, the study analyzed the biocompatibility, tissue structure, and calcification...

In recent years, the use of Left Ventricular Assist Devices (LVAD) in the treatment of heart failure has been increasingly widespread. Not only do they provide circulatory support for patients, but the reverse...

In recent years, the use of Left Ventricular Assist Devices (LVAD) in the treatment of heart failure has been increasingly widespread. Not only do they provide circulatory support for patients, but the reverse...

CONCLUSIONS: Both in vitro and in vivo experiments demonstrate that our precisely designed patch provided a stable and effective solution for reducing progressive axial elongation in HM. By leveraging nanotechnology, electrical stimulation, and scleral reinforcement surgery, this study offers a groundbreaking approach with significant implications for both scientific research and clinical practice. Our strategy paves the way for enhanced surgical outcomes in HM treatment, offering a promising...

In recent years, the use of Left Ventricular Assist Devices (LVAD) in the treatment of heart failure has been increasingly widespread. Not only do they provide circulatory support for patients, but the reverse...