General

Result of Surgical Treatment for Active Infective Endocarditis at the Aortic Position

Herein, we retrospectively review our experience with surgical treatment of active aortic valve infective endocarditis, particularly aortic annular abscess, and central nervous system complications. From 2012 to 2021, 46 consecutive patients underwent surgery during the active phase of infective endocarditis, 25 of which were performed at the aortic position. One patient died early (<30 days) due to low output syndrome and another 2 patients who were never discharged died because of general...
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Aortic Valve Replacement

The aortic valve is a semilunar valve with three leaflets, which lies at the junction of left ventricle and aorta. It allows unidirectional blood flow from the left ventricle to the aorta and the rest of the body. Because of the highly complex and sophisticated cellular and molecular functions, the thin valve leaflet can withstand extreme mechanical and hemodynamic forces with every cardiac cycle. Various factors including age and congenital defects can compromise the normal valvular function...
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Importance of in situ thermal stability after surgical implantation of acellular scaffold

Acellular scaffold is mainly composed of collagen, which is sensitive to temperature. The denaturation of collagen, whether immediately or lately after implantation will lead to profound influence on the micro-structure, biological activities of acellular scaffold, and tissue repairing process. However, the in situ thermal stability of acellular scaffold had rarely been investigated previously. In this study, the thermal stability of two acellular scaffolds, acellular bovine pericardium (S1) and...
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